I spent some time over the Christmas break updating the Drug Discovery Resources pages on Fragment-Based screening, adding new vendors and updating the physicochemical profiles. I've also added some discussion on the elaboration/optimisation of fragments.

The pages are

Fragment-Based Screening
Building a Fragment Collection
Available Fragment Collections
Profiles of Fragment Collections
Fragment-Based Screening Published Hits

The published fragments contains details of fragments that have been reported as hits in the literature, this database now has over 1500 entries culled from over 310 publications directed at nearly 220 different molecular targets using 26 different detection technologies.

It could be argued that published fragment hits perhaps gives us an insight into the best fragments to include in library design.