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Cambridge MedChem Consulting

20th SCI/RSC Medicinal Chemistry Symposium

20th SCI/RSC Medicinal Chemistry Symposium on 8 - 11 September 2019 at Churchill College, Cambridge.

Abstract deadline: Friday 9th November 2018

The organising committee wishes to solicit late-breaking, high impact medicinal chemistry talks to finalise the scientific programme. Potential contributions should be communicated to the secretariat at conferences@soci.org by Friday 9th November 2018. A number of conference places will be reserved for poster presenters and contributions are invited from the whole field of medicinal chemistry. Those presenting a poster may also elect to advertise their poster via oral presentation of a single slide 'flash' poster. Detailed procedures and submission deadlines for poster abstracts will be provided in the second announcement.

More details

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3rd RSC BMCS Medicinal Chemistry Symposium on Macrocycles

The full agenda for the Macrocycles 2018 meeting 8th-9th October 2018 is now available and it looks to be a great meeting.

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Full details of the meeting and registration is available online here http://www.maggichurchouseevents.co.uk/bmcs/macrocycles_2018-online%20registration.htm.

20th SCI/RSC Medicinal Chemistry Symposium

The first circular for the 20th SCI/RSC Medicinal Chemistry Symposium (aka the Cambridge MedChem Meeting) has been announced. This is also a call for abstracts for both oral and poster submissions. Potential contributions should be communicated to the secretariat at conferences@soci.org by Friday 9th November 2018.

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You can download the full details of the meeting here PDF.

A number of outstanding talks have already been confirmed.

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RSC-BMCS / RSC-CICAG Artificial Intelligence in Chemistry

The lineup for the RSC-BMCS / RSC-CICAG conference on Artificial Intelligence in Chemistry has been announced.

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Twitter hashtag - #RSC_AIChem

09.00 Registration, refreshments, and exhibition
10.00 Presentation title to be confirmed Marwin Segler, Benevolent AI, UK
10.30 Presentation title to be confirmed Nadine Schneider, Novartis, Switzerland
11.00 Refreshments, exhibition and posters
11.30 Keynote: What I learned about machine learning - revisited Bob Sheridan, Merck, USA
12.30 Lunch, posters and exhibition
14.00 Molecular de novo design through deep learning Ola Engkvist, AstraZeneca, Sweden
14.30 Scaling de novo design, from single target to disease portfolio Wilhem van Hoorn, Exscientia, UK
15.00 Refreshments, posters and exhibition
15.30 Investigating clusters in solvent data using K-means Ella Gale, University of Bristol, UK
16.00 Deep learning and chemical data Colin Batchelor, Royal Society of Chemistry, UK
16.30 Automation, analytics and AI Darren Green, Molecular Design UK, RD Platform Technology & Science, GlaxoSmithKline, UK
17.00 Drinks reception
18.00 Close

Register here.

Friday, 15th June 2018, Royal Society of Chemistry at Burlington House, London, UK
Poster closing date is 13th April
Bursary closing date is 3rd May

Macrocycles 2018: 3rd RSC BMCS Medicinal Chemistry Symposium on Macrocycles

Take note of the closing dates for abstracts

Applications for oral and poster presentations are welcome. Posters will be displayed throughout the meeting and applicants should indicate whether they wish to be considered for a flash oral presentation when submitting an abstract (two minutes, single slide).The closing dates of 28th February (oral) and 8th August (poster).

PhD Student and Post-Doc Conference Bursaries

Did you know that most BMCS sponsored meetings have a number of bursaries available for PhD and post-doctoral students? Normally up to a value of £250, these awards help to cover registration and travel costs. Preference will be given to members of the RSC (and meeting co-sponsors if applicable), especially those who are selected to give posters.

Macrocycles 2018 meeting #BMCS_Macrocycles

Monday-Tuesday, 8th-9th October 2018, GlaxoSmithKline, Stevenage, UK

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The objective of this symposium is to promote scientific interaction between scientists with a shared interest in the field of Macrocycles. This area is responsible for a growing number of therapeutic approaches and development candidates, all of which go ‘beyond the rule-of–five’. As a researcher in this field, come along to hear about the latest advances and also to share in some of the secrets of discovering therapeutic agents which go beyond Lipinski’s rules.

Full details and application forms are here http://www.maggichurchouseevents.co.uk/bmcs/Macrocycles-2018.htm.

Macrocycles 2018: 3rd RSC BMCS Medicinal Chemistry Symposium on Macrocycles

First announcement for the Macrocycles 2018 meeting #BMCS_Macrocycles

Monday-Tuesday, 8th-9th October 2018, GlaxoSmithKline, Stevenage, UK

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The objective of this symposium is to promote scientific interaction between scientists with a shared interest in the field of Macrocycles. This area is responsible for a growing number of therapeutic approaches and development candidates, all of which go ‘beyond the rule-of–five’. As a researcher in this field, come along to hear about the latest advances and also to share in some of the secrets of discovering therapeutic agents which go beyond Lipinski’s rules.

Applications for oral and poster presentations are welcome. Posters will be displayed throughout the meeting and applicants should indicate whether they wish to be considered for a flash oral presentation when submitting an abstract (two minutes, single slide).The closing dates of 28th February (oral) and 8th August (poster).

Full details and application forms are here http://www.maggichurchouseevents.co.uk/bmcs/Macrocycles-2018.htm.

Neglected and Tropical Diseases Session at the 19th Cambridge MedChem Meeting

Update

I'm delighted to report that over 200 people have now watched the video online, looks like it was a valuable resource.


One of the nice things about my job is I get the chance to take part in some truly inspiring events. Last month I had the honour of chairing a session on Neglected and Tropical Diseases at the 19th Cambridge MedChem Meeting. In an effort of extend the exposure of the brilliant science undertaken in this important therapeutic area the conference organisers arranged for this to be a live webinar. The session was also recorded and is now available online.

https://youtu.be/XLOCFrjrMEY

This is a recording of the Neglected and Tropical Diseases Session at the 19th Cambridge MedChem Meeting, 11-13 September 2017. The speakers are Kelly Chibale (Univ of Capetown), Christoph Boss (Actelion), Rob Young (GlaxoSmithKline), Jonathan Large (LifeArc) and Charles Mowbray (DNDI).

Please feel free to share. #19thCamMedChem.

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29th Symposium on Medicinal Chemistry in Eastern England

The Symposium on Medicinal Chemistry in Eastern England, known colloquially as the "Hatfield MedChem" meeting, is a highly successful, long-standing, one-day meeting which runs annually will be held 26 April 2018 09:30-17:00, Hatfield, United Kingdom

The Organising Committee are inviting abstract submissions for both oral and poster presentation. Please download an abstract template from the event website and return it the secretariat. Closing dates for submissions are:

24th November 2017 for oral abstracts
23rd February 2018 for poster abstract

19th Cambridge MedChem Meeting

The 19th RSC / SCI Medicinal Chemistry Symposium (#19thCamMedChem) takes place 10th-13th September 2017 at Churchill College, Cambridge, UK. This biennial meeting is one of the highlights of the drug discover calendar. Each meeting we try to enhance the scientific programme and this time there will be a live webcast of one of the sessions.

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New for 2017 - Live Webcast Session on Neglected Tropical Diseases
Tuesday, 12th September Afternoon (13-30pm start).
Session Chair: Chris Swain, Consultant, UK

Introduction to the Neglected Tropical Diseases (NTD) session
Kelly Chibale, University of Capetown, South Africa
PI4K inhibitors that target multiple life cycle stages of the human malaria parasite
Kelly Chibale, University of Capetown, South Africa
Discovery and characterization of ACT-451840: an antimalarial drug with a novel mechanism of action
Christoph Boss, Actelion, Switzerland

Refreshments and short film clips

Rapid discovery of non-covalent inhibitors of DprE1, a novel and exciting target to treat Mycobacterium tuberculosis: impact of medicinal chemistry on an open source collaboration
Rob Young, GlaxoSmithKline, UK
Potent, selective and orally efficacious inhibitors of Plasmodium falciparum Protein Kinase G (PfPKG)
Jon Large, LifeArc, UK
First disclosure of a new oral development candidate for the treatment of visceral and cutaneous leishmaniasis
Charlie Mowbray, DNDi (Drugs for Neglected Diseases initiative), Switzerland
Closing remarks for NTD session
Charlie Mowbray, DNDi, Switzerland

The meeting is now fully booked but we hope that scientists around the world will be able to watch the presentations live using this link

LiveStream.

Please feel free to share this link.




11th Biological and Medicinal Chemistry Postgraduate Symposium

Friday 8th December 2017, Department of Chemistry, University of Cambridge, Cambridge

Closing date for abstract submission is 15th September 2017

The Biological and Medicinal Chemistry Sector (BMCS) of the Royal Society of Chemistry will be hosting its 11th postgraduate symposium for PhD students and postdoctoral workers researching in biological or medicinal chemistry and related areas. The event will be held in the Department of Chemistry at the University of Cambridge on Friday 8th December 2017. Researchers working in these areas are invited to participate. Registration will start at 9:00 am with talks beginning at 10:00 am. The day will consist of 11 oral presentations (8 student and 3 keynote) plus a Flash Poster section. Each 20 minute student talk will be followed by 10 minutes for questions.

This is a fantastic meeting for anyone interested in medicinal chemistry and drug discovery, this event is FREE but all attendees should register as soon as possible and no later than the 1st December 2017.

19th RSC / SCI Medicinal Chemistry Symposium

The 19th RSC / SCI Medicinal Chemistry Symposium takes place 10th-13th September 2017 at Churchill College, Cambridge, UK. This biennial meeting is one of the highlights of the drug discover calendar. The full lecture timetable can be downloaded here.

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Call for Posters
Contributions from the whole field of medicinal chemistry are invited. Flash presentation sessions are planned which will involve a two-minute presentation of poster highlights. Poster abstract submissions should be sent to the secretariat by 16th April if you wish to take advantage of the early-bird registration fee and indicate whether or not you would like to be included for consideration in the flash presentation session. The final deadline for submission of posters is 21st July.

Registration is now open and delegates are encouraged to book early to ensure places at this very popular meeting. Discounted rates are available to RSC and SCI student members, and some student bursaries are available. Applications are invited from PhD and post-doctoral students studying at European academic institutions, preferably members of the RSC, SCI or EFMC. Those submitting abstracts for poster presentation will be favoured. To apply for a student bursary, please complete and return the bursary application form by 21st July.

The BMCS Mastering MedChem III: 3rd RSC-BMCS symposium on mastering medicinal chemistry

This meeting is aimed at all those who wish to become better drug hunters and heed warnings from the past. (22 March 2017 09:00-19:00, Cardiff Bay, United Kingdom).

In the main there are two types of drug discovery programmes: those that hit serious problems and those that are going to hit serious problems. The difference between success and failure is how we, as medicinal chemists, tackle and resolve the problems

Sounds a great meeting both for those starting out in their careers and for those looking to pick up new tips.

28th symposium on Medicinal Chemistry in Eastern England

28th symposium on Medicinal Chemistry in Eastern England, Thursday 27th April 2017, The Fielder Centre, Hatfield, Hertfordshire, UK
Organised by RSC-BMCS (Royal Society of Chemistry – Biological and Medicinal Chemistry Sector)

More details

Programme

09.00 Registration, refreshments and exhibition
Session chair: Adrian Hall, UCB
09.30 Opening remarks
Nicole Hamblin, GlaxoSmithKline
09.35 From phenotypic hit to a validated target for tuberculosis
Robert Bates, GlaxoSmithKline
10.10 Discovery of potent inhibitors of the lysophospholipase autotaxin
Prit Shah, Cancer Research Technology
10.45 Refreshments and exhibition
11.15 Development of Tesirine: a clinical antibody-drug conjugate pyrrolobenzodiazepine payload: medicinal chemistry at the frontier between small molecules and biologics
Arnaud Tiberghien, Spirogen
11.50 NMR conformational analysis in molecular design – case studies and impact
Martin Packer, AstraZeneca
12.25 Highly potent cell-penetrant inhibitors of the KEAP1-NRF2 protein-protein interaction via X-ray fragment screening
Charlotte Griffiths-Jones, Astex Pharmaceuticals
13.00 Lunch and exhibition


Session Chair: Simon Ward, University of Sussex
14:05 Selective on-target chemical probes of protein-protein interactions
Alessio Ciulli, University of Dundee
14.40 Solid state studies of a preclinical candidate in a CRO environment: the importance of de-risking early
Russell Scammell, Charles River
15.15 Refreshments and exhibition
15.45 Drug discovery case study
Tom Miller, Shire
16.20 Optimisation of a series of novel smoothened inhibitors
Matilda Bingham, RedX
16.55 Concluding remarks
17.00 Close

Fragments 2017

Fragment-based screening is now a well established methodology for the identification of leads for drug discovery and the aim of the 6th RSC-BMCS Fragment-based Drug Discovery meeting will be to continue the focus on case studies in Fragment-based Drug Discovery that have delivered compounds to late stage medicinal chemistry, preclinical or clinical programmes.

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6th RSC-BMCS Fragment-based Drug Discovery meeting
Sunday to Tuesday, 5th to 7th March 2017
at Parkhotel Schönbrunn, Vienna, Austria

Full details and registration are online.

Cheminformatics for Drug Design: Data, Models & Tools

Still a few places left at the Cheminformatics for Drug Design: Data, Models & Tools meeting organised by SCI's Fine Chemicals Group and RSC's Chemical Information and Computer Applications Group has been extended.

Imperial War Museum, Duxford, UK Wednesday 12 October 2016

Full details are available here https://www.soci.org/Events/Display-Event?EventCode=FCHEM481

Sounds an excellent meeting and you will have a chance to look around the aircraft at the Duxford Imperial War Museum.

Two conferences that might be of interest

Event FBLD 2016 (Fragment-based Lead Discovery Conference 2016)
Place Cambridge, Massachusetts, USA
Dates 9th-12th October 2016
Website http://www.ysbl.york.ac.uk/fbld/2016/   
Poster abstracts Closing date is 30th September
Event Fragments 2017 - 6th RSC-BMCS Fragment-based Drug Discovery meeting
Dates Sunday to Tuesday, 5th to 7th March 2017
Place Parkhotel Schönbrunn, Vienna, Austria
Websites http://www.maggichurchouseevents.,co.uk/bmcs
also http://www.rsc.org/events/detail/23352/fragments-2017-7th-rsc-bmcs-fragment-based-drug-discovery-meeting
 

Cheminformatics for Drug Design: Data, Models & Tools

I’ve just heard that the poster deadline for the Cheminformatics for Drug Design: Data, Models & Tools meeting organised by SCI's Fine Chemicals Group and RSC's Chemical Information and Computer Applications Group has been extended.

Imperial War Museum, Duxford, UK Wednesday 12 October 2016

Full details are available here https://www.soci.org/Events/Display-Event?EventCode=FCHEM481

Sounds an excellent meeting and you will have a chance to look around the aircraft at the Duxford Imperial War Museum.

19th RSC/SCI Medicinal Chemistry Symposium

I’m delighted to highlight the first announcement of the 19th RSC/SCI Medicinal Chemistry Symposium to be held in Cambridge in September 2017. Europe’s premier biennial Medicinal Chemistry event, focusing on first disclosures and new strategies in medicinal chemistry.

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Click here for more details

Solutions for Drug-Resistant Infections Meeting

SDRI 2017 is a multi-disciplinary scientific conference for the Asia Pacific region focused on Solutions for Drug Resistant Infections. This inaugural conference theme is New Drugs for Drug-Resistant Infections. The conference will take place at the Brisbane Convention and Exhibition Centre in Australia from 3 - 5 April, 2017.

The program is expected to attract 400 international participants and will provide a fantastic forum for researchers and industry representatives working in the space of microbiology, virology, parasitology, genomics, pharmacology and medicinal chemistry, to network and discuss new ways to solve the global challenge of drug-resistant infections. Our goal for SDRI 2017 is to lead a concerted discussion to set three priorities and guide research efforts towards global solutions for drug resistance research.

Conference themes:

  • Antimicrobial drug discovery
  • Improvements to existing anti-infective agents and repurposing
  • New Drug Targets
  • Alternate therapies
  • Navigating the pipeline
  • International Models and Funding
  • Vector control and vaccines

International keynote speakers confirmed:

  • Professor Dame Sally Davies DBE FMedSci FRS, Chief Medical Officer for England
  • Professor Ramanan Laxminarayan, Director for Center for Disease Dynamics, Economics & Policy (CDDEP), Washington and Vice-President for Research & Policy at Public Health Foundation of India (PHFI)

More details and registration


RSC symposium on Late Stage Functionalization for Synthesis and Medicines

RSC symposium on Late Stage Functionalization for Synthesis and Medicines

Date Monday, 5th December 2016 Place Mathematical Institute, Andrew Wiles Building, Oxford, U Organisers RSC-BMCS (Royal Society of Chemistry – Biological and Medicinal Chemistry Sector)

Late Stage Functionalization (LSF) holds the potential to revolutionise the logic of chemical synthesis and open new ways to prepare novel natural products and medicines. The introduction of important chemical groups for medicinal chemistry in the very last steps of the synthesis through LSF could also dramatically speed up the preparation of NCEs and have a major impact on drug discovery. The availability of new powerful catalytic chemistries showing a high degree of functional group tolerance and that can be performed under mild conditions offer tremendous opportunities for chemists to access new molecules that cannot be made easily by conventional approaches.

Cheminformatics for Drug Design: Data, Models & Tools

A joint meeting Organised by SCI's Fine Chemicals Group and RSC's Chemical Information and Computer Applications Group

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18th SCI/RSC Medicinal Chemistry Symposium

18th SCI/RSC Medicinal Chemistry Symposium Sunday 13 - Wednesday 16 September 2015 Churchill College, Cambridge , UK

Europe’s premier biennial Medicinal Chemistry event, focusing on first disclosures and new strategies in medicinal chemistry. Reflecting current trends in medicinal chemistry and pharmaceutical research, the theme of the conference will be ‘Drugging the Undruggable’.

A number of conference places will be reserved for poster presenters and contributions are invited from the whole field of medicinal chemistry. Those presenting a poster may also elect to advertise their poster via oral presentation of a single slide ‘flash’ poster. In addition to traditional plenary talks the organising committee wishes to solicit short talks (20 minutes) describing highly impactful but possibly less complete episodes of medicinal chemistry.

Further Information SCI Conference Dept, 14/15 Belgrave Square, London, SW1X 8PS T: + 44 (0)20 7598 1561 E: conferences@soci.org W: www.soci.org

Biological and MedChem Meeting

I just got details of an interesting meeting in Cambridge, UK later this year.

BMCS PG Symposium 2013 Flyer

The registration form is here

17th RSC/SCI Medicinal Chemistry Symposium

The registrations are coming in for the forthcoming 17th RSC/SCI Medicinal Chemistry Symposium to be held in Cambridge UK (8-11 Sept 2013). Book early to avoid disappointment.

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Full details of the scientific programme are available here together with the registration form.

17th RSC/SCI Medicinal Chemistry Symposium

The latest details of the forthcoming 17th RSC/SCI Medicinal Chemistry Symposium to be held in Cambridge UK (8-11 Sept 2013) are now available.

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Full details of the scientific programme are available here together with the registration form.

16th SCI/RSC Medicinal Chemistry Symposium

The deadline for the early bird rates ends soon for the 16th SCI/RSC Medicinal Chemistry Symposium to be held Sunday 11 -14 September 2011 Churchill College, Cambridge, UK.

The 16th SCI-RSC Medicinal Chemistry Symposium will focus on first disclosures and new strategies in medicinal chemistry. Reflecting current trends in medicinal chemistry and pharmaceutical research, the theme of the conference will be The Path Forward: Collaboration or Competition? The scientific programme features lectures on Enzyme Inhibitors, Ligands for Receptors and Ion Channels plus a Hot Topic late breaker session. In addition the meeting has a number of talks addressing key Enabling Processes and Technologies for the future of Medicinal Chemistry. There will also be Poster Sessions with a number of posters selected for short talks.

Full details are here

RSC MedChem School

The details of the RSC MedChem School that will be held 4-8 July 2011 at Burleigh Court Conference Centre, Loughborough University are now online. Early bird registration is available until April 1st.

Full details can be found on the RSC website here.

The residential training school focusses on current thinking in drug discovery and will take place at the Burleigh Court Conference Centre, Loughborough University. The course is directed primarily at graduate and post doctoral chemists with 1-4 years experience in the field of drug research. Final year PhD students in pharmacy and organic chemistry contemplating a career in medicinal chemistry will also find the course of use.

16th SCI/RSC Medicinal Chemistry Symposium

The flyer containing details of and the application form for the 16th SCI/RSC Medicinal Chemistry Symposium to be held Sunday 11 -14 September 2011 Churchill College, Cambridge, UK is now available for download:

FINAL CIRCULAR and APPLICATION FORM

The 16th SCI-RSC Medicinal Chemistry Symposium will focus on first disclosures and new strategies in medicinal chemistry. Reflecting current trends in medicinal chemistry and pharmaceutical research, the theme of the conference will be The Path Forward: Collaboration or Competition? The scientific programme features lectures on Enzyme Inhibitors, Ligands for Receptors and Ion Channels plus a Hot Topic late breaker session. In addition the meeting has a number of talks addressing key Enabling Processes and Technologies for the future of Medicinal Chemistry. There will also be Poster Sessions with a number of posters selected for short talks

Call for Posters

Contributions from the whole field of medicinal chemistry are invited. Please submit A4 abstracts of your poster presentation to jacqui.colgate@soci.org and indicate whether you are willing to be upgraded to a poster talk. Deadline for submissions: 27 May 2011.

RSC MedChem School

The RSC Medicinal Chemistry Summer School, for the last 40 years regarded as the pre-eminent industry training course for medicinal chemists, is due to take place 4-8th July 2011 at Burleigh Court Conference Centre, Loughborough University.  It brings together cross-industry and cross-discipline  practitioners to provide lectures, tutorials , workshops and case-studies illustrating modern drug discovery.   This will provides an excellent training opportunity for young medicinal chemists, a refresher for those more experienced, or an introduction to drug design thinking for any scientist working in cross-functional discovery teams.

The flyer and application form can be downloaded here.

RSC MedChem School

The details of the RSC MedChem School that will be held 4-8 July 2011 at Burleigh Court Conference Centre, Loughborough University are now online. Early bird registration is available until April 1st.

Full details can be found on the RSC website here.

The residential training school focusses on current thinking in drug discovery and will take place at the Burleigh Court Conference Centre, Loughborough University. The course is directed primarily at graduate and post doctoral chemists with 1-4 years experience in the field of drug research. Final year PhD students in pharmacy and organic chemistry contemplating a career in medicinal chemistry will also find the course of use.

16th RSC-SCI Medicinal Chemistry Symposium

The first circular for the 16th RSC-SCI Medicinal Chemistry Symposium, 11-14 September 2011, Churchill College, Cambridge, UK is now available here.

Scientifc Program includes:-

  • Strategies to success - H-PGDS inhibitors for the treatment of inflamatory disorders, Sukanthini Thurauratnam, Sanofi -Aventis

  • Discovery on next generation glucokinase activators, Mike Waring, AstraZeneca

  • Inhalation by design, Paul Glosson, Pfizer

  • Bromodomains a new class of epigenetic targets for small molecule drug discovery, Jason Witherington, GSK

  • GPCR Structure based drug design using stabilised receptors(StaRs), Miles Congreve, Heptares

  • GS-9350: a novel pharmacoenhancer, Lianhong Xu, Gilead Sciences