Help design inhibitors of the SARS-CoV-2 main protease
Are you a medicinal chemist currently locked out of your lab?
Why not take a break from writing papers/reports and lend your expertise to this effort, https://covid.postera.ai/covid. They have identified 60 fragment hits and are asking for insight in what should be made next.
We are now asking for your help in designing new inhibitors based on these initial fragment hits: the exceptionally dense readout suggests countless opportunities for growing and merging, and we need many sharp brains to sift through them; it is also what makes us believe that potency can be directly achieved.
The first round of submissions will be reviewed tonight and the selected molecules will be made by Enamine.