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Cambridge MedChem Consulting

OpenSource Antibiotics

I just thought I’d highlight a new project I’m involved with.

Open Source Antibiotics ( is intended to be a platform for a collaborative effort towards antibiotic discovery.


The first projects have been initiated

Mur Ligase ( and the background to these exciting targets can be found on the wiki page.

This also provides details of the first two fragment screens.




What we want now is for people to join in and suggest the next round of fragments that should be screened. Ideally these should be commercially available but if people want to design, make and submit their own fragments we would be happy to screen them.

If you feel appropriate, we would appreciate any publicity on this exciting new project