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Cambridge MedChem Consulting

Susceptibility testing in antibacterial drug R&D

This looks like an interesting webinar for all those interested in antibiotics research

Susceptibility testing in antibacterial drug R&D

Presentation 1: Pre-clinical antimicrobial susceptibility testing: considerations and challenges (Dee Shortridge):

  • Steps for developing an in vitro susceptibility test for your lead compound
  • Studies needed to characterize your compound
  • Points to consider if your compound is not typical

Presentation 2: Pitfalls and opportunities of susceptibility testing in clinical trials of new antibiotics (Rafael Cantón):

  • The introduction of new antimicrobials needs antimicrobial susceptibility testing to define their profile and the alignment with regulators.
  • Susceptibility testing data are also used to define both clinical and PK/PD breakpoints.
  • Moreover, they can be used to recognize wild type populations and anticipate emergence or resistance.

This is organised by the Global Antibiotic Research & Development Partnership (GARDP) https://gardp.org.

The Global Antibiotic Research & Development Partnership (GARDP) accelerates the development and access of treatments for drug-resistant infections. Together with private, public and non-profit partners, GARDP works to preserve the power of antibiotics for generations to come.