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Cambridge MedChem Consulting

Fluorine Fragment Library

Key Organics have expanded the BIONET Fluorine Fragment Library which now includes 719 fluorinated fragments. All 719 fragments in the Fluorine Fragment Library have been analysed by 19F NMR and 1H NMR for:

  • Structure verification
  • Purity
  • Measured solubility in PBS buffer ≥ 100μM
  • Aggregation.

The calculated physicochemical properties of the library are shown below. They have also been filtered using PAINS and Lilly MedChem rules.


There are more Fragment Collections described here.