Very interesting opportunity https://www.ukri.org/opportunity/epsrc-centres-for-doctoral-training/?. Total fund £324,000,000.s

Applications are now open for 12-week summer placements projects available at Diamond starting in June 2022. Absolutely fantastic opportunities.

https://www.diamond.ac.uk/Careers/Students/Summer-Placement/2022-Summer-Placements1.html

Diamond Light Source is the UK’s national synchrotron. It works like a giant microscope, harnessing the power of electrons to produce bright light that scientists can use to study anything from fossils to jet engines to viruses and vaccines.

As someone who had to make a major career change due to personal circumstances I really recommend this sort of webinar that has been organised by the RSC.

Career choices when faced with changes of life

Join Career Consultants Cath Elmer and John Toscano who will spend an evening helping you give your working lives a well-deserved health check! Together we will look at some of the reasons career circumstances can change - out of choice or otherwise. We will discuss some of the career theories behind our decision-making processes to help us assess where we are and be better prepared for the future. This interactive event will be of interest whatever stage of your career.

Thursday 15th April 6:00-8:00 pm

Link https://www.rsc.org/events/detail/46366/career-choices-when-faced-with-changes-of-life.

The Early Career MedChem Workshop is a pre-meeting workshop taking place on the Sunday afternoon before the 20th SCI/RSC Medicinal Chemistry Symposium, Churchill College, Cambridge, Sunday 8 - Wednesday 11 September 2019.

It is aimed at early career (up to 5 years’ experience) medicinal chemists. Registration for this event will be at no additional cost to the main meeting.

The workshop will consist of a team-based exercise around a virtual medicinal chemistry programme and will offer participants:

• Training in advanced medicinal chemistry
• Testing out leadership/decision making skills
• Networking between potential future leaders of different organisations
• Introductions of possible future collaborators from pharma, CRO, charity and SME sectors
• Opportunity for informal interaction with experienced medicinal chemists workshop facilitators who will be open to questions around their own experiences
• Attendance at the full 20th SCI/RSC Medicinal Chemistry Symposium including lectures on a full range of drug targets, key enabling processes and technologies

Feedback from previous events has been excellent for this unique learning experience.

Also note there are student bursaries to help fund attendance at this event, email conferences@soci.org for more information.

One of the highlights of the SCI/RSC Cambridge MedChem Meetings the Early Career MedChem Workshop, a satellite workshop consisting of a team-based exercise around a virtual medicinal chemistry programme will be held on the Sunday afternoon prior to this event, aimed at early career (up to 5 years’ experience) medicinal chemists. Registration for this event will be at no additional cost to the main meeting, Read the flyer here.

Registration is on the 20th SCI / RSC Medicinal Chemistry Symposium website

The Royal Society of Chemistry Medicinal Chemistry Residential School takes place 2 - 7 June 2019, Loughborough, United Kingdom is a fantastic opportunity for anyone starting out or contemplating a career in Drug Discovery.

The school is designed for graduate and post-doctoral chemists with 1-5 years’ experience in the field of drug research. Drug discovery is an interdisciplinary subject so delegates from biological or computational backgrounds will benefit from attendance at the school. In addition, final year PhD students from pharmaceutical or organic chemistry contemplating a career in drug discovery are also encouraged to attend.

The course includes the following topics:

• Target Validation
• Computational Chemistry
• Biological Mechanisms
• Pharmacokinetics and Drug Metabolism
• Screening of New Compounds
• Patents
• Molecular Biology in Medicinal Chemistry
• Exploiting a Chemical Lead
• Combinatorial Chemistry and Molecular Diversity
• Case Histories of Drug Discovery
• Toxicology in Drug Discovery
• Pharmaceutical Considerations in Drug Development
• Structure-guided Drug Design
• Physical Properties and Quantitative Structure-Activity Relationships
• Hints and Tips in Medicinal Chemistry

Full details here http://www.rsc.org/events/detail/33379/medicinal-chemistry-residential-school-2019.

I've been a tutor at the RSC MedChem School on a number of occasions and I can say this is an excellent opportunity for scientists new to drug discovery to benefit from an understanding of all aspects of the drug discovery process, from target and hit identification, through ADME and computational chemistry, to patents and safety studies.

The 2017 Medicinal Chemistry Residential School takes place 11 - 16 June, Loughborough UK, it is always very popular so well worth signing up early.

The 2017 Residential School will take place over 5 days and content is delivered by experts in the field from industry and academia. The programme includes lectures focusing on the fundamental principles of drug discovery, hands-on tutorials allowing delegates to put into practice what they have learnt and case histories from previous drug discovery projects. The programme will also include an evening lecture from a distinguished speaker. Throughout the week course tutors and speakers will be available for informal discussion and there will be plenty of opportunities to network with the broad range of academic and industrial researchers in attendance.

During 2016 Global Health are running a series of webinars on the subject of compound design. The programme for future meetings is available below (the agenda will develop through the year).

Date Agenda (& timing of each item in the recording when available)

21st Jan 2016

Introduction to meetings, Mark Gardner Application of PK Tools in the optimisation of a series for the treatment of leishmaniasis, Gavin Whitlock, Sandexis, working with DNDi Hints and tips to working with DataWarrior, Isabelle Giraud, Actelion, slides Isabelle Giraud, DataWarrior demonstration" Recording

25th Feb 2016

Visceral leishmaniasis TCP & screen sequence, Charlie Mowbrary, DNDi Malaria Target Candidate Profiles, stage gates and implications for successful malaria drug discovery, Paul Willis, MMV Registration

17th Mar 2016 "DataWarrior advanced data analysis, Isabelle Giraud, Actelion Using the RSC Medicinal Chemistry Toolkit in Drug Discovery Projects, Andy Davis, AZ The RSC Medicinal Chemistry Toolkit is a free suite of resources to support the day-to-day work of drug discovery scientists.  It was developed to provide difficult-to-access, but industry-validated tools in a portable format. The presentation  will show with worked examples,  how the RSC Medicinal Chemistry Toolkit (Apple only) can be used to  support design strategy thinking and structure-activity optimization. https://itunes.apple.com/gb/app/medicinal-chemistry-toolkit/id910073742?mt=8" Registration

21st Apr 2016

Free data pipelining tool KNIME in compound design & analysis Introduction to KNIME & use cases in drug discovery – further details tbd Registration

There are more details here.

I’ve just been sent details of a new medicinal chemistry course.

Medicinal Chemistry: The Molecular Basis of Drug Discovery

This course explores how to bring a drug from concept to market, and how a drug's chemical structure relates to its biological function. The course opens with an introduction to the drug approval process. This introduction combines the social, economic, and ethical aspects of drug discovery. Topics include how diseases are selected for treatment, the role of animal testing, and the costs of various discovery phases. The course then focuses on the scientific side of drug discovery. Topics include how drugs interact with biological molecules, drug absorption and elimination, and the discovery of weakly active molecules and their optimization into viable drugs.

The course starts 10 March, it is estimated the course will require 6-8 hours per week and runs for 7 weeks. The course was organised by Erland Stevens who wrote the medchem textbook Medicinal Chemistry: The Modern Drug Discovery Process.