fragment-based screening
Updated Fragment Collections
05/05/11 08:27
I’ve just updated two pages.
Fragment Collections on which I’ve added a couple of additional suppliers, and Fragment collection profiles on which I’ve added the profile of the TimTec collection and updated the collections from the existing vendors. It seems that as the collections evolve more of the collections are starting to look like they were designed rather than simply applying cutoffs (MWt etc) to an existing sample collection. We are starting to see less aromatic compounds and more consideration to the 3D structure.
Fragment Collections on which I’ve added a couple of additional suppliers, and Fragment collection profiles on which I’ve added the profile of the TimTec collection and updated the collections from the existing vendors. It seems that as the collections evolve more of the collections are starting to look like they were designed rather than simply applying cutoffs (MWt etc) to an existing sample collection. We are starting to see less aromatic compounds and more consideration to the 3D structure.
Updated Fragment Collection Profiles
16/10/10 08:49
Several companies have kindly sent me updated copies of the structure files for their fragment collections.
Full details are on the Fragment Collection Profiles page. Read More...
Full details are on the Fragment Collection Profiles page. Read More...
Fragment Screening
14/10/10 12:55
I’ve just updated the page on fragment collection profiles Read More...
Fragment Screening
30/09/10 08:38
Just completed a project to help design a fragment library for Selcia to be used with their proprietary fragment screening technology CEFrag.
A poster will be presented at the FBLD2010 meeting in Philadelphia in October
A poster will be presented at the FBLD2010 meeting in Philadelphia in October
Fragment-Based Screening
13/02/10 08:37
Updated the list of commercially available fragment libraries.
Updates
07/12/09 08:56
I’ve added a sections on fragment-based screening, solubility and updated the section on metabolism.